Evaluation of the Influence of Diabetic Control on Vitamin B12 Levels in Children and Adolescents with Type 1 Diabetes

Document Type : Original Article

Authors

1 Department of Pediatrics, Faculty of Medicine, Suez Canal University, Egypt.

2 Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt.

3 Department of Pediatrics, Faculty of Medicine, Port Said University, Egypt.

Abstract

Aim: The study aims to evaluate the influence of diabetic control on vitamin B12 levels. Patients and Methods: The study was conducted on 40 children diagnosed with type 1 Diabetes Miletus, who attended El Arab school health insurance unit in Port-Said City. Serum vitamin B12 and diabetic profile (fasting, random blood sugar, and HbA1c) were sampled and values below the limit of the blank are reported as < 50.0 pg/mL or < 36.9 pmol/L and values above the measuring range are reported as > 2000 pg/mL or > 1476 pmol/L. HbA1C measurement was used for the assessment of diabetic control. Results: The average age of patients was 9 years. The mean FPG was 142 mg/dL, the mean RBS was 221 mg/dL, and the mean HbA1c was 10.13%. The mean duration of diabetes was 4±2 years. All studied patients showed normal vitamin B12 levels. The mean serum vitamin B12 level was 687pg/m and there was no statistically significant correlation between B12 and HbA1c. Conclusion: The mean HbA1c among type 1 diabetic patients who attended El Arab School health insurance unit in Port-Said City was 10.13%. There is no relation between serum vitamin B12 level and duration of diabetes or diabetic control.
 

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