Halim, H., Gad, M., Nada, H., Ali, M. (2024). Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts. Suez Canal University Medical Journal, 27(2), 0-0. doi: 10.21608/scumj.2024.345566
Halim M. Halim; Mohammed EM. Gad; Hesham A. Nada; Mohamed AM. Ali. "Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts". Suez Canal University Medical Journal, 27, 2, 2024, 0-0. doi: 10.21608/scumj.2024.345566
Halim, H., Gad, M., Nada, H., Ali, M. (2024). 'Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts', Suez Canal University Medical Journal, 27(2), pp. 0-0. doi: 10.21608/scumj.2024.345566
Halim, H., Gad, M., Nada, H., Ali, M. Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts. Suez Canal University Medical Journal, 2024; 27(2): 0-0. doi: 10.21608/scumj.2024.345566
Microneedling-Assisted Topical Bleomycin versus Cryotherapy in the Treatment of Anogenital Warts
1Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Suez Canal University, Egypt.
2Dikirnis General Hospital, Mansoura, Egypt.
Abstract
Background:Anogenital warts treatment has always been a demanding entity. Although several therapeutic options exist, no single modality is completely effective in its treatment rather than preventing recurrence. Aim: To assess the effectiveness ofmicroneedling-assisted topical bleomycin versus cryotherapy in the treatment of anogenital warts. Methods:This trial involved 36 patientswho were split into two groups. Group (A): bleomycin (n=18). Group (B): cryotherapy (n=18). In group (A), microneedling was performed on the lesion followed by spraying of bleomycin (1 U/mL) every two weeks for a total of four sessions. In group (B), Cryotherapy was employed at a two-week interval for a maximum of 4 sessions. Results:By the end of sessions, 15(83.3%) patients in the bleomycin group and 11(61.1%) patients in the cryotherapy group showed complete response of all the warts with a statistically significant difference (P = 0.039).Also, the percentage of improvement was significantly higher in warts with lower duration among both groups. After 6 months, Recurrence was reported only in two (13.3%) patients in the bleomycin group compared to five (45.5%) in the cryotherapy group with a statistically insignificant difference (p=0.095). Conclusion: In treating anogenital warts, microneedling-assisted topical bleomycin is more effective than cryotherapy.
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