Abdelmaogood, A. (2022). Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?. Suez Canal University Medical Journal, 25(1), 1-12. doi: 10.21608/scumj.2022.204002
Asmaa K Abdelmaogood. "Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?". Suez Canal University Medical Journal, 25, 1, 2022, 1-12. doi: 10.21608/scumj.2022.204002
Abdelmaogood, A. (2022). 'Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?', Suez Canal University Medical Journal, 25(1), pp. 1-12. doi: 10.21608/scumj.2022.204002
Abdelmaogood, A. Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?. Suez Canal University Medical Journal, 2022; 25(1): 1-12. doi: 10.21608/scumj.2022.204002
Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?
Department of Clinical & Chemical Pathology, Faculty of Medicine, Suez Canal University, Ismailia Egypt; Research fellow, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Abstract
MS is a rare neurodegenerative disease with an immunopathological background. Although, it has a rather low global prevalence, it can be considered among one of the most common youth disabling disorders that are not related to trauma. It is also classified as a complex disease with many susceptibility genes incriminated in its etiology and prognosis. In addition, several well identified and extensively studied environmental factors are implicated as vitamin D metabolism & ultraviolet B (UVB) exposure, Epstein Barr virus (EBV) infection, smoking and morbid obesity. The infamous relationship between Vitamin D and MS has been an area of extensive research in many aspects; pathophysiology, disease course, prognosis and even response to treatment.