Mukbel, M., Ahmed, A. (2012). Endoscopic and Histological Evaluation of Chronic Gastritis in Yemen. Suez Canal University Medical Journal, 15(1), 40-48. doi: 10.21608/scumj.2012.54675
Murad A Mukbel; Al-Haimi M Ahmed. "Endoscopic and Histological Evaluation of Chronic Gastritis in Yemen". Suez Canal University Medical Journal, 15, 1, 2012, 40-48. doi: 10.21608/scumj.2012.54675
Mukbel, M., Ahmed, A. (2012). 'Endoscopic and Histological Evaluation of Chronic Gastritis in Yemen', Suez Canal University Medical Journal, 15(1), pp. 40-48. doi: 10.21608/scumj.2012.54675
Mukbel, M., Ahmed, A. Endoscopic and Histological Evaluation of Chronic Gastritis in Yemen. Suez Canal University Medical Journal, 2012; 15(1): 40-48. doi: 10.21608/scumj.2012.54675
Endoscopic and Histological Evaluation of Chronic Gastritis in Yemen
Department of Internal Medicine, Faculty of Medicine and Health Science, Sana’a University, Yemen
Abstract
Aim: To study the prevalence of H. pylori infection; identify the endoscopic findings associated with H. pylori infection and to determine relation between endoscopic and histological findings of chronic gastritis in the presence of H. pylori. Patients and Methods: One hundred fifty six consecutive patients with dyspepsia referred for upper gastrointestinal endoscopy were enrolled in this study. Assessment of H. pylori was based on the urease test and histological examination of gastric biopsy specimens. Results: One hundred and fifty-six consecutive patients (127 males, 29 females) with a mean age of 38.6 years (range 18 to 67years) were studied. H. pylori were positive in 125 patients (80.1%) and negative in 31 patients (19.9%). Gastritis was found in 96 patients (61.5%) of all patients. H. pylori were found in 93.8% (90/96) of patients with gastritis and 58.3% (35/60) of patients without gastritis. Association between H. pylori infection and gastritis was statistically significant (P<0.001). The following endoscopic findings were identified in the patient infected with H. pylori:erythema, edema, exudate, raised erosion, antral nodularity and rugal atrophy. The specificity of macroscopic diagnosis in comparison to histological diagnosis of erosive gastritis, atrophic gastritis, nodular gastritis and erythematous/exudative gastritis were high 100%, 98%, 93 % and 79% respectively. Conclusions: i) Prevalence of H. pylori infection is high and is strongly associated with the development of chronic gastritis. ii) Endoscopic findings are reliable indicator of H. pylori associated gastritis.
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