Harraz, M. (2014). Programmed Necrosis-mediated Cell Death and Disease: Recent Advances. Suez Canal University Medical Journal, 17(1), 1-9. doi: 10.21608/scumj.2014.45311
Maged M Harraz. "Programmed Necrosis-mediated Cell Death and Disease: Recent Advances". Suez Canal University Medical Journal, 17, 1, 2014, 1-9. doi: 10.21608/scumj.2014.45311
Harraz, M. (2014). 'Programmed Necrosis-mediated Cell Death and Disease: Recent Advances', Suez Canal University Medical Journal, 17(1), pp. 1-9. doi: 10.21608/scumj.2014.45311
Harraz, M. Programmed Necrosis-mediated Cell Death and Disease: Recent Advances. Suez Canal University Medical Journal, 2014; 17(1): 1-9. doi: 10.21608/scumj.2014.45311
Programmed Necrosis-mediated Cell Death and Disease: Recent Advances
Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Abstract
Cell death classification has been based on morphological characteristics for decades. Modern advances in molecular technology enabled us to explore cell death pathways on a level of unprecedented detail. While necrosis has been considered a negative unpreventable form of cell death, recent findings demonstrate that a subtype of necrosis, namely necroptosis, is a regulated programmed process. Hence, therapeutic intervention to inhibit necroptosis-mediated loss of cells in a disease process is possible. This review highlights recent advances in programmed necrosis (necroptosis) and its potential relationship to human disease.
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