El Merry, M., Ali, H., Yehia, M., Saber, M. (2025). Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.. Suez Canal University Medical Journal, 28(2), 6-12. doi: 10.21608/scumj.2025.419587
Mohammed Ahmed El Merry; Hesham Hegazy Ali; Mohamed Khaled Yehia; Mohamed Yousef Saber. "Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.". Suez Canal University Medical Journal, 28, 2, 2025, 6-12. doi: 10.21608/scumj.2025.419587
El Merry, M., Ali, H., Yehia, M., Saber, M. (2025). 'Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.', Suez Canal University Medical Journal, 28(2), pp. 6-12. doi: 10.21608/scumj.2025.419587
El Merry, M., Ali, H., Yehia, M., Saber, M. Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.. Suez Canal University Medical Journal, 2025; 28(2): 6-12. doi: 10.21608/scumj.2025.419587
Correlation between Hypertensive Retinopathy and Sever-ity of Coronary Artery Disease in Hypertensive Patients.
1Cardiology department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
2Cardiology department, Al Ahrar Teaching Hospital, Zagazig, Egypt
Abstract
Background: Hypertensive retinopathy (HR) reflects systemic microvascular damage, but its role as an independent risk factor of coronary artery disease (CAD) severity remains underexplored. Aim: this research aims to investigate the association between degree of hypertensive retinopathy (HR) and retinal arteriosclerosis (AS) with CAD severity in hypertensive patients. Methods: In this cross-sectional study, 100 hypertensive patients (aged 35–75 years) with angina and confirmed CAD underwent coronary angiography and assessment of the intensity of CAD was assessed by Gensini score and a correlation with fundoscopic examination to assess the severity of hypertensive retinopathy and retinal arteriosclerosis by using Scheie classification was done. Statistical testing included Spearman’s correlation and multivariate linear regression. Results: hypertensive retinopathy and retinal arteriosclerosis stages showed strong positive correlations with CAD severity (rho = 0.72 and 0.65, respectively; p < 0.001). In multivariate analysis, each hypertensive retinopathy stage increases independently predicted an 8.4-point rise in Gensini score (95% CI: 6.2–10.6; p < 0.001), outperforming traditional risk factors (age, smoking, cholesterol). Conclusion: Hypertensive retinopathy is a strong, independent predictor of CAD severity. Retinal examination may enhance risk stratification in hypertensive patients, offering a non-invasive tool for early CAD detection.
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