Mohamed, M., Nour-Eldein, H., Saudi, R. (2023). Prevalence of Cognitive Impairment among Type 2 Diabetes Mellitus Patients Attending Family Medicine Clin-ic in Suez Canal University Hospital. Suez Canal University Medical Journal, 26(9), 51-63. doi: 10.21608/scumj.2023.324133
Madyha M. Mohamed; Hebatallah Nour-Eldein; Rabab A. Saudi. "Prevalence of Cognitive Impairment among Type 2 Diabetes Mellitus Patients Attending Family Medicine Clin-ic in Suez Canal University Hospital". Suez Canal University Medical Journal, 26, 9, 2023, 51-63. doi: 10.21608/scumj.2023.324133
Mohamed, M., Nour-Eldein, H., Saudi, R. (2023). 'Prevalence of Cognitive Impairment among Type 2 Diabetes Mellitus Patients Attending Family Medicine Clin-ic in Suez Canal University Hospital', Suez Canal University Medical Journal, 26(9), pp. 51-63. doi: 10.21608/scumj.2023.324133
Mohamed, M., Nour-Eldein, H., Saudi, R. Prevalence of Cognitive Impairment among Type 2 Diabetes Mellitus Patients Attending Family Medicine Clin-ic in Suez Canal University Hospital. Suez Canal University Medical Journal, 2023; 26(9): 51-63. doi: 10.21608/scumj.2023.324133
Prevalence of Cognitive Impairment among Type 2 Diabetes Mellitus Patients Attending Family Medicine Clin-ic in Suez Canal University Hospital
Department of Family Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Abstract
Background: Dementia risk is increased by 50% in people with type 2 diabetes mellitus (T2DM). The gradual loss of most cognitive functions leads to increased dependency and social isolation. Aim: This study aimed to assess the prevalence of cognitive impairment among T2DM patients compared to non-diabetic patients and to determine the associated factors that increase the risk of cognitive impairment among T2DM patients. Subjects and Methods:A comparative cross-sectional study was conducted at the family medicine outpatient clinic, Suez Canal University Hospital, Egypt, between October 2019 and October 2020. A simple random sampling of 400 participants was categorized into two groups, T2DM patients (200) and non-diabetic patients (200). The Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) tools were used to assess the cognitive function. Results: The prevalence of cognitive impairment was 50% in diabetic patients as measured by MoCA,compared to 26.5 % in the non-diabetic group (P <0.05). In specific cognitive domains (orientation, calculation, recall, and language), diabetic patients showed significantly lower scores compared with non-diabetic patients (P <0.05). Education and socioeconomic status were significant positive predictors of MMSE score; while age, BMI, duration of diabetes, FBG, HbA1c, and LDL were negative predictors of cognitive impairment tested by MMSE among T2DM patients(p < 0.05). Conclusion: Diabetic patients were more likely to have cognitive impairment compared to patients without diabetes. Diabetes had a particularly negative impact on the following cognitive functions: orientation, calculation, recall, and language.
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