Background: Long-term use of contact lenses may lead to various changes in the tear layer, conjunctiva, and cornea depending on the oxygen-permeability of lenses. Contact lens-induced- hypoxia and corneal edema caused by acidosis. Aim: to evaluate the effect of long-term, soft contact lens wear on corneal endothelium and corneal thickness aiming at improving the quality of vision in contact lens wearers and keeping their corneas healthy as considered a precious refractive surface of the eye. Patients and Methods: This cross-sectional case-control study included 96 eyes (48 right and 48 left eyes) of 48 participants randomly selected with the age group between 18-30 years, 30 female, and 18 male. Participants were divided into two groups (case and control group) each of which included 48 eyes. Results: There is a statistically significant difference between both groups regarding BCVA (p < /em>= 0.001). while, the changes in CCT in contact lens wearers were not statistically significant (p < /em> =0.9) unlike the morphological parameters as CD (P <0.001), CV (p- =0.004), SD (p- =0.001) which shows statistically significant changes. There was no significant difference as regards (CCT), the hexagonal appearance of the cell (HEX%), and average cell area (AVG) between the contact lens wearer and control group. The baseline means of endothelial cell density in group 1 was 2911 ± 244 cells/mm2, while group 2 was 2610 ± 173 cells/mm2. There was a statistically significant difference between the case and control group as regards endothelial cell density (ECD) (p < /em> <0.001). The mean of (CV%) in group 1 was (28 ± 6), while in group 2 was (28 ± 6). There was a statistically significant difference between the contact lens wearer and the control group as regards (CV%) (p < /em> = 0.004). Conclusion: Long-term soft contact lens use (> 1 year) affects cell density (CD) and morphological features (coefficient of variation (CV), pleomorphism, and polymegathism).
Mansour, E., Elgharieb, M. E., & Moawad, E. M. (2023). Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness. Suez Canal University Medical Journal, 26(9), 21-28. doi: 10.21608/scumj.2023.323930
MLA
Esraa Mansour; Mervat E. Elgharieb; Ehab M. Moawad. "Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness", Suez Canal University Medical Journal, 26, 9, 2023, 21-28. doi: 10.21608/scumj.2023.323930
HARVARD
Mansour, E., Elgharieb, M. E., Moawad, E. M. (2023). 'Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness', Suez Canal University Medical Journal, 26(9), pp. 21-28. doi: 10.21608/scumj.2023.323930
VANCOUVER
Mansour, E., Elgharieb, M. E., Moawad, E. M. Effect of Long-Term Soft Contact Lens Wearing on Corneal Endothelial Cells and Central Corneal Thickness. Suez Canal University Medical Journal, 2023; 26(9): 21-28. doi: 10.21608/scumj.2023.323930
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