Adly, O., El-Sayed, M., Ibrahim, M., Shalaby, A. (2023). Functional Capacity and Outcome of Auto-transplantation of Thyroid Gland Tissue after Total Thyroidectomy for Benign Thyroid Disease. Suez Canal University Medical Journal, 26(4), 0-0. doi: 10.21608/scumj.2023.305531
Osama A. Adly; Mohammed A. El-Sayed; Mohammed S. Ibrahim; Ahmed R. Shalaby. "Functional Capacity and Outcome of Auto-transplantation of Thyroid Gland Tissue after Total Thyroidectomy for Benign Thyroid Disease". Suez Canal University Medical Journal, 26, 4, 2023, 0-0. doi: 10.21608/scumj.2023.305531
Adly, O., El-Sayed, M., Ibrahim, M., Shalaby, A. (2023). 'Functional Capacity and Outcome of Auto-transplantation of Thyroid Gland Tissue after Total Thyroidectomy for Benign Thyroid Disease', Suez Canal University Medical Journal, 26(4), pp. 0-0. doi: 10.21608/scumj.2023.305531
Adly, O., El-Sayed, M., Ibrahim, M., Shalaby, A. Functional Capacity and Outcome of Auto-transplantation of Thyroid Gland Tissue after Total Thyroidectomy for Benign Thyroid Disease. Suez Canal University Medical Journal, 2023; 26(4): 0-0. doi: 10.21608/scumj.2023.305531
Functional Capacity and Outcome of Auto-transplantation of Thyroid Gland Tissue after Total Thyroidectomy for Benign Thyroid Disease
1Plastic Surgery Unit, General Surgery Department, Faculty of Medicine, Suez Canal University, Egypt
2Department of General Surgery, Faculty of Medicine, Suez Canal University, Egypt
3Pediatric Surgery Unit, General Surgery Department, Faculty of Medicine, Suez Canal University, Egypt
4General Surgery Department, Mansoura New General Hospital, Egypt
Abstract
Background:Total thyroidectomy is the operation of choice today in the treatment of benign thyroid diseases affecting both lobes. When this operation is done precisely, the patients will survive safely with the lowest complications. Aim: The aim of this work was to solve the problems of patients undergoing total thyroidectomy for benign thyroid diseases. Also was to evaluate the survival and the functional capacity of auto-transplanted thyroid gland tissue after total thyroidectomy for benign thyroid disease. Patients and Methods: A prospective case study was conducted on 30 patients who were candidates for total thyroidectomy for benign thyroid disease followed by auto-transplantation of thyroid gland tissue in the thigh muscle, studying the outcome and functional capacity of the transplanted tissue. Results: Median TSH of studied patients showed a marked decrease from 1-month post operation till 12-month post-operation,after 12 months post-implantation, this study showed; 22 patients (73.3%) full functioning implant (i.e., normal thyroid function tests), 3 patients (10%) partial functioning implant and 5 patients (16.7%) failed implant (i.e., low T3 and T4 and very high TSH). Conclusion: Thyroid auto-transplantation is a promising technique that requires further study, as 73.3% of the patients in this study had fully functioning grafts at the end of the study. Body weight and operative time had no significant correlation with the grafts’ functional outcome. Worse results were achieved in patients with Graves’ disease compared with the patients with multinodular goiter. The young patients and the weight of the implanted tissue of 10 g had a good impact on the result of transplantation.
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