Evaluation of Sentinel Lymph Node Mapping in Uterine Cancer Staging

Document Type : Original Article

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Department of Surgery, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Abstract

Background: Lymphatic mapping recently emerged as a promising new strategy and is increasingly being adopted by gynecologic oncology practices worldwide. The sentinel lymph node is a technique used to properly detect nodal metastases hence improving staging accuracy with the subsequent proper application of adjuvant therapy. Aim: to evaluate of the accuracy of sentinel lymph node biopsy using a patant blue dye in endometrial and cervical malignancies. Patients and Methods: Twenty-six patients, diagnosed with endometrial cancers stage (I/II) by MRI, and three patients, diagnosed with cervical cancers stage (Ia/IIa) by MRI, were enrolled in the study. Results: Sentinel lymph node(s) were successfully identified in 18 patients (69.2%) with endometrial carcinoma and one case with cancer cervix. The sensitivity of sentinel Lymph node mapping in the detection of lymph node metastasis was 100% with a negative predictive value of 100% and 0% false negative rate. There was a statistically significant inverse relation between sentinel lymph node detection and tumor grading. There was a statistically significant relation between sentinel lymph node detection and both cervical involvement and positive lymph node metastasis. Conclusion: Sentinel Lymph node mapping in cases of early-stage endometrial cancer is a good option to avoid overtreatment with unnecessary removal of more lymph nodes, which may result in an increase in perioperative adverse effects.
 

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Suez Canal University Medical Journal
Volume 26, Issue 1
January 2023
Pages 70-75

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