Home Articles List Article Information
Suez Canal University Medical Journal
Journal Archive
Volume Volume 28 (2025)
Volume Volume 27 (2024)
Volume Volume 26 (2023)
Volume Volume 25 (2022)
Volume Volume 24 (2021)
Volume Volume 23 (2020)
Volume Volume 22 (2019)
Volume Volume 21 (2018)
Volume Volume 20 (2017)
Volume Volume 19 (2016)
Volume Volume 18 (2015)
Volume Volume 17 (2014)
Volume Volume 16 (2013)
Volume Volume 15 (2012)
Volume Volume 14 (2011)
Volume Volume 13 (2010)
Tawfik, N., Romeia, S., Youssef, N., Atwa, M. (2022). Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?. Suez Canal University Medical Journal, 25(4), 54-60. doi: 10.21608/scumj.2022.270509
Noha Tawfik; Samar GA Romeia; Nahed Youssef; Mona A. Atwa. "Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?". Suez Canal University Medical Journal, 25, 4, 2022, 54-60. doi: 10.21608/scumj.2022.270509
Tawfik, N., Romeia, S., Youssef, N., Atwa, M. (2022). 'Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?', Suez Canal University Medical Journal, 25(4), pp. 54-60. doi: 10.21608/scumj.2022.270509
Tawfik, N., Romeia, S., Youssef, N., Atwa, M. Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?. Suez Canal University Medical Journal, 2022; 25(4): 54-60. doi: 10.21608/scumj.2022.270509

Mean Platelet Volume in Psoriasis: Is it a New Prognostic Indicator?

Article 7, Volume 25, Issue 4, December 2022, Page 54-60  XML PDF (350.81 K)
Document Type: Original Article
DOI: 10.21608/scumj.2022.270509
View on SCiNiTO View on SCiNiTO
Authors
Noha Tawfik email orcid 1; Samar GA Romeia1; Nahed Youssef2; Mona A. Atwaorcid 1
1Department of Dermatology, Venereology, and Andrology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
2Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
Abstract
Background: Psoriasis is a chronic multifactorial inflammatory autoimmune disease. It has significant impacts on health and quality of life. Platelets play a major role in the pathogenesis of psoriasis, and the activated platelets increase the migration of leukocytes to the skin, increasing the release of inflammatory cytokines. Recent studies showed that MPV (mean platelet volume) could be used as an indicator of platelet function and activation. Previous studies assessed only the value of MPV in psoriatic patients without studying its relationrelationship < /ins> with different treatment modalities. Aim:To study the changes in MPV in psoriasis patients and its association with disease severity after treatment with NB-UVB. Patents and Methods: 25 psoriatic patients were assessed for MPV and psoriasis area and severity index score (PASI) before treatment, during treatment and after treatment with NBUVB (three times weekly for 3 months). Results:The relation between MPV and PASI was statistically insignificant before and after treatment. The PASI score was significantly decreases after treatment. Conclusion: This study demonstrated insignificant correlation between MPV levels and PASI score of psoriatic patients before and after NBUVB phototherapy. Further studies on larger number of patients were needed to assess the relation between MPV and psoriasis.
 
Keywords
Psoriasis; Mean Platelet Volume; NB-UVB
Main Subjects
Clinical Research (Medical)
Statistics
Article View: 186
PDF Download: 349