Ghanem, A., Abou-Ali, M., Hussein, A., Anwar, A., Abu-Elela, S. (2021). Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection. Suez Canal University Medical Journal, 24(1), 29-40. doi: 10.21608/scumj.2021.159779
Ahmed M Ghanem; Mustafa Abou-Ali; Ahmed H Hussein; Ahmed M Anwar; Sameh T Abu-Elela. "Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection". Suez Canal University Medical Journal, 24, 1, 2021, 29-40. doi: 10.21608/scumj.2021.159779
Ghanem, A., Abou-Ali, M., Hussein, A., Anwar, A., Abu-Elela, S. (2021). 'Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection', Suez Canal University Medical Journal, 24(1), pp. 29-40. doi: 10.21608/scumj.2021.159779
Ghanem, A., Abou-Ali, M., Hussein, A., Anwar, A., Abu-Elela, S. Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection. Suez Canal University Medical Journal, 2021; 24(1): 29-40. doi: 10.21608/scumj.2021.159779
Evaluation of the Outcome of the Use of 2% Lidocaine Irrigation in the Prevention of Abdominal Surgical Site Infection
Department of Surgery, Faculty of Medicine, Suez Canal University Hospitals and Medical School, Ismailia, Egypt
Abstract
Background:Surgical site infection (SSI) is the third most common nosocomial infection, associated with higher morbidity and mortality rates as well as increased cost and prolonged hospital stay for patients. Lidocaine, in addition to being a readily available and accessible local anesthetic, has shown antimicrobial and fungicidal activity. Objectives: Assessing the outcome of using 2% lidocaine irrigation in the prevention of abdominal SSI in grade II (clean-contaminated), Grade III (contaminated) wounds. Subjects and Methods: This prospective randomized clinical trial included patients who underwent elective and emergency abdominal surgeries in the Department of General Surgery at Suez Canal University Hospitals. The participants were randomly divided in two groups: A study group, who received sterile saline plus Lidocaine 2%. And a control group, who received sterile saline only to compare the 30-day postoperative infection outcomes among them. Results: 56.8% of participants were males. The mean age of participants was 48.88 ± 10.18 years. The study group patients had statistically significant lower incidents of SSI than the control group (p=0.03). The overall incidence of SSI was 38.6%. The most prevalent sign of the SSI was pus in 35.3% and in 76.5% of the patients’ SSI lasted for two weeks. There was no statistically significant difference between both groups regarding their hospital stay duration, laboratory measures, and other postoperative complications. Conclusions:2% lidocaine application before skin closure in grade II and grade III wounds decreased the incidence of SSI) in patients undergoing abdominal surgery.
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