Assessment of Serum 25- Hydroxycholecalciferol Level in Patients with Recalcitrant Palmoplantar Warts

Tawfik, Noha; Hussein, Hadeer I; Hassan, Ranya M; Atwa, Mona A

doi:10.21608/scumj.2020.124696

Assessment of Serum 25- Hydroxycholecalciferol Level in Patients with Recalcitrant Palmoplantar Warts

Document Type : Original Article

Authors

¹ Department of Dermatology and Venereology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

² Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt

10.21608/scumj.2020.124696

Abstract

Background: Viral warts are benign growths that result from an infection of epidermal or mucosal cells with the human papillomavirus. Epidemiological studies have demonstrated a link between vitamin D deficiency and increased rates of infectious diseases and their resistance to treatment. Such a link between vitamin D level and wart recalcitrance is yet to be revealed. To the best of our knowledge, there were no previous studies conducted to reveal the possible relationship between vitamin D and recalcitrant warts. Aim: To assess serum vitamin D levels in patients with recalcitrant palmoplantar warts. Subjects and Methods:A cross-sectional study conducted on two groups. The first group included 35 patients with recalcitrant palmoplantar warts, the second group included 35 healthy volunteers matched for age, sex. Serum vitamin D level was measured. Results: A total of 78 participants were enrolled in this study, including 30 males and 48 females, distributed among the 3 groups. There was no statistically significant difference in serum vitamin D levels between the studied groups. Its mean level in the recalcitrant group was 26.03 ng/ml, while in the responsive group it was 29.36 ng/ml and reached 25.15ng/ml in the control group. Conclusion: low serum vitamin D levels do not seem to increase the susceptibility of warts to get resistant to treatment.

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